The Role of Bariatric Surgery in Abdominal Organ Transplantation-the Next Big Challenge?

Obes Surg. 2017 Oct;27(10):2696-2706. doi: 10.1007/s11695-017-2854-8.

Abstract

Obesity is linked to inferior transplant outcome. Bariatric surgery (BS) is an established treatment of morbid obesity. We provide an overview on BS in the field of kidney (KT) and liver transplantation (LT). In end-stage renal disease (ESRD) and KT patients, BS seems safe and feasible. Complication rates were slightly higher compared to the non-transplant population, whereas weight loss and improvement of comorbidities were comparable. Sleeve gastrectomy (SG) was the preferred procedure before KT and superior to gastric bypass (GB) in regard to mortality and morbidity. If conducted after KT, both procedures showed comparable results. BS before LT was associated with high complication rates, in particular after GB. Albeit distinct complications, SG conducted after LT showed the best results. Immunosuppression (IS) changes after BS were rare.

Keywords: Bariatric surgery; Kidney transplantation; Liver transplantation; Obesity; Organ transplantation.

Publication types

  • Review

MeSH terms

  • Bariatric Surgery / adverse effects
  • Bariatric Surgery / methods*
  • Comorbidity
  • Gastrectomy / adverse effects
  • Gastrectomy / methods
  • Gastric Bypass / adverse effects
  • Gastric Bypass / methods
  • Humans
  • Kidney Failure, Chronic / epidemiology
  • Kidney Failure, Chronic / surgery*
  • Kidney Transplantation* / methods
  • Kidney Transplantation* / statistics & numerical data
  • Liver Diseases / epidemiology
  • Liver Diseases / surgery*
  • Liver Transplantation* / methods
  • Liver Transplantation* / statistics & numerical data
  • Obesity, Morbid / epidemiology
  • Obesity, Morbid / surgery*
  • Treatment Outcome
  • Weight Loss