Particulate catalysts with streamline shapes have important impacts on fluid-related reactions, and they need to be properly characterized. However, utilization of streamline-shaped catalysts for heterogeneous catalysis has remained an unexplored area due to the lack of easy-to-use techniques to produce such shaped catalysts, especially at the small length scale of the submicron to micron regime. Herein, we report our recent development of a class of prototype nanocatalysts with streamline shapes. In this research, the kinetic control is adapted to obtain streamline-shaped supports, followed by functionalizing such supports with catalytically active metal nanoclusters (e.g., Au, Pd, Pt, and Ag or their combinations) in a stepwise manner. Advantages related to the streamline morphology of catalysts have been demonstrated with a number of solid-solution systems such as alcohol oxidation, olefin hydrogenation, and Suzuki-Miyaura coupling. We believe these findings will promote new research on the design and synthesis of functional materials with additional fluid-advanced features.