Small-molecule antagonists of the immune checkpoint pathways: concept to clinic

Future Med Chem. 2017 Aug;9(12):1305-1308. doi: 10.4155/fmc-2017-0107. Epub 2017 Aug 3.
No abstract available

Keywords: PD-1 pathway; VISTA; antagonist; checkpoint inhibitor; immuno-oncology; immunomodulator; immunotherapy; orally bioavailable; protein–protein interaction; small molecule.

Publication types

  • Editorial
  • Portrait

MeSH terms

  • Animals
  • Humans
  • Mice
  • Neoplasms / drug therapy*
  • Neoplasms / immunology*
  • Small Molecule Libraries / chemistry
  • Small Molecule Libraries / pharmacology*

Substances

  • Small Molecule Libraries