We present for the first time an adjacent dehydrogenative homocoupling and cyclodehydrogenation reaction of mesityl groups to form a synthetic nanoribbon on Cu(110). Submolecular resolution scanning tunneling microscopy (STM) observations and density functional theory (DFT) calculations confirm the formation of an ethylene (-CH[double bond, length as m-dash]CH-) unit or an aromatic six-membered ring group.