A case of bronchiolitis obliterans organising pneumonia associated with SAPHO (synovitis-acne-pustulosis-hyperostosis-osteitis) syndrome

Fawad Hameed; Henry Steer

doi:10.1136/bcr-2017-219822

A case of bronchiolitis obliterans organising pneumonia associated with SAPHO (synovitis-acne-pustulosis-hyperostosis-osteitis) syndrome

BMJ Case Rep. 2017 Aug 1:2017:bcr2017219822. doi: 10.1136/bcr-2017-219822.

Authors

Fawad Hameed¹, Henry Steer²

Affiliations

¹ Department of Respiratory Medicine, Musgrove Park Hospital, Taunton and Somerset NHS Foundation Trust, Taunton, UK.
² Department of Respiratory Medicine, Gloucestershire Royal Hospital, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK.

Abstract

A 57-year-old woman with SAPHO (synovitis-acne-pustulosis-hyperostosis-osteitis) syndrome presented with recurrent episodes of pneumonia. She was treated with multiple courses of antibiotics with no success. The transbronchial biopsy undertaken via bronchoscopy revealed organising pneumonia (OP). She was treated with steroids and responded well with full clinical recovery and normalisation of her chest X-ray.To our knowledge, this is the first reported case of OP in association with SAPHO syndrome. This case report highlights the importance of considering OP in patients with SAPHO syndrome who present with chest infection.

Keywords: bronchiolitos; interstitial lung disease; musculoskeletal syndromes; pneumonia (respiratory medicine).

Publication types

Case Reports

MeSH terms

Acquired Hyperostosis Syndrome / complications*
Administration, Oral
Biopsy
Cryptogenic Organizing Pneumonia / diagnosis*
Cryptogenic Organizing Pneumonia / drug therapy*
Cryptogenic Organizing Pneumonia / etiology
Female
Humans
Middle Aged
Steroids / therapeutic use
Treatment Outcome

Substances

Steroids