Preparation and characterization of hybrid double network chitosan/poly(acrylic amide-acrylic acid) high toughness hydrogel through Al3+ crosslinking

Xiancai Jiang; Nanping Xiang; Jinquan Wang; Yulai Zhao; Linxi Hou

doi:10.1016/j.carbpol.2017.06.003

Preparation and characterization of hybrid double network chitosan/poly(acrylic amide-acrylic acid) high toughness hydrogel through Al³⁺ crosslinking

Carbohydr Polym. 2017 Oct 1:173:701-706. doi: 10.1016/j.carbpol.2017.06.003. Epub 2017 Jun 2.

Authors

Xiancai Jiang¹, Nanping Xiang¹, Jinquan Wang¹, Yulai Zhao¹, Linxi Hou²

Affiliations

¹ School of Chemical Engineering, Fuzhou University, Fuzhou 350108, People's Republic of China.
² School of Chemical Engineering, Fuzhou University, Fuzhou 350108, People's Republic of China. Electronic address: lxhou@fzu.edu.cn.

PMID: 28732916
DOI: 10.1016/j.carbpol.2017.06.003

Abstract

Development of bio-based hydrogels with good mechanical properties is of great importance for their excellent biocompatibility and biodegradability. In this paper, chitosan (CS) based double network (DN) hydrogel was prepared by dissolving CS in AlCl₃·6H₂O aqueous solution instead of acetic acid solution. After dissolving acrylic amide (AM), acrylic acid (AA), N, N'-methylenebisacrylamide and 2-hydroxy-4'-(2-hydoxyethoxy)-2-methylpropiophenone were added into the CS/Al³⁺ solution and the CS/PAMAA-Al³⁺ DN hydrogel was prepared by UV polymerization. The hybrid physical and chemical crosslinked network hydrogels were prepared. The tensile and compression properties of CS/PAMAA-Al³⁺ DN hydrogel were studied. The results showed that the CS/PAMAA-Al³⁺ DN hydrogels have high toughness, stretch-ability, and excellent shape recovery properties. The CS/PAMAA-Al³⁺ DN hydrogel could show the tensile strength of 0.54MPa and elongation at break of 2203.7%. These properties arise from the dynamic ionic interaction between Al³⁺ and CS/PAMAA macromolecular chains.

Keywords: Chitosan; Dissolving; Double network hydrogel; Mechanical properties; Toughness.