The assessment of laboratory parameters in children with fever and febrile seizures

Brain Behav. 2017 May 15;7(7):e00720. doi: 10.1002/brb3.720. eCollection 2017 Jul.

Abstract

Objective: The aim of the research paper was to assess selected laboratory results in children with fever without seizures and febrile seizure.

Materials and methods: The paper presents an analysis of a group of 306 children aged 6 months - 5 years who were admitted with diagnosed fever without seizures and febrile seizures in Specialized Health Care Centre for Mother and Child in Poznan between 1st January 2008 and 31st December 2009. Out of the diagnostics procedures performed in children the following ones were taken into consideration: BCC and CRP.

Results: Of the analyzed group of 306 children, 59.48% were boys and 40.52% were girls. In the studied group 61.93% were boys and control group 56.15% were boys. Mean age of admitted children was 22 months. In the study group mean body temperature was 39.0°C and in the control group 38.6°C. A statistically significant difference was found between body temperature of study and control group (p = .005). The mean C-reactive protein level in the study group was 15.73 mg/L and in the control group 58.20 mg/L. There was a statistically significant difference (p < .001). There was a statistically significant difference between the number of lymphocytes and neutrophils (p < .001). There was also a statistically significant difference between the number of hemoglobin, hematocrit and platelets.

Conclusions: The study showed that children with FS, had statistically significant higher neutrophils level compared to those with fever without seizures. The number of lymphocytes was lower in children with FS than in children with fever without seizures.

Keywords: children; febrile seizures; fever; laboratory results.

MeSH terms

  • Blood Cell Count
  • Body Temperature / physiology*
  • Child, Preschool
  • Diagnostic Tests, Routine
  • Female
  • Fever / blood*
  • Fever / physiopathology
  • Hematocrit
  • Humans
  • Infant
  • Male
  • Seizures, Febrile / blood*
  • Seizures, Febrile / physiopathology