Oxytocin Mobilizes Midbrain Dopamine toward Sociality

Alexandre Charlet; Valery Grinevich

doi:10.1016/j.neuron.2017.07.002

Oxytocin Mobilizes Midbrain Dopamine toward Sociality

Neuron. 2017 Jul 19;95(2):235-237. doi: 10.1016/j.neuron.2017.07.002.

Authors

Alexandre Charlet¹, Valery Grinevich²

Affiliations

¹ Centre National de la Recherche Scientifique and University of Strasbourg, Institute of Cellular and Integrative Neurosciences, 67084 Strasbourg, France; University of Strasbourg Institute for Advanced Study (USIAS), 67083 Strasbourg, France. Electronic address: acharlet@unistra.fr.
² Schaller Research Group on Neuropeptides, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; CellNetwork Cluster of Excellence, University of Heidelberg, 69120 Heidelberg, Germany; Central Institute of Mental Health, 68159 Mannheim, Germany. Electronic address: v.grinevich@dkfz-heidelberg.de.

PMID: 28728017
DOI: 10.1016/j.neuron.2017.07.002

Abstract

Oxytocin and dopamine possess significant overlap in the modulation of life-essential behaviors. Here, Xiao et al. (2017) show that the activity of dopamine neurons of the ventral tegmental area and the substantia nigra is finely tuned by axonal release of oxytocin.

Publication types

Review

MeSH terms

Animals
Dopamine / metabolism*
Humans
Mesencephalon / metabolism*
Neurons / metabolism
Oxytocin / metabolism*
Substantia Nigra / metabolism*
Ventral Tegmental Area / metabolism*

Substances

Oxytocin
Dopamine