Selective inhibition of host cell signaling for rotavirus antivirals: PI3K/Akt/mTOR-mediated rotavirus pathogenesis

Virulence. 2018 Jan 1;9(1):5-8. doi: 10.1080/21505594.2017.1356539. Epub 2017 Aug 18.

Author

Jason Kindrachuk¹

Affiliation

¹ a Laboratory of Emerging and Re-Emerging Viruses , Department of Medical Microbiology, University of Manitoba , Winnipeg , MB , Canada.

No abstract available

Keywords: autophagy; cell signaling; drug repurposing; pathogenesis; rotavirus.

Publication types

Editorial
Comment

MeSH terms

Antiviral Agents
Autophagy / drug effects
Humans
Phosphatidylinositol 3-Kinases*
Proto-Oncogene Proteins c-akt*
Rotavirus
TOR Serine-Threonine Kinases

Substances

Antiviral Agents
MTOR protein, human
Proto-Oncogene Proteins c-akt
TOR Serine-Threonine Kinases