Gallbladder cancer (GC) is a rare malignancy but represents almost 50% of all biliary tract cancer. Biliary cancers are highly fatal malignancies with a 5-year survival rate of 17.6% (2007 to 2013). The prognosis of gallbladder cancer is poor due to the aggressive tumor biology, late presentation, complicated anatomic position, and advanced stage at diagnosis. Locally advanced and metastatic disease treatment is with palliative chemotherapy. Conversely, early-stage is potentially curative with surgical resection followed by adjuvant therapy.
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