Simple platelet markers: Mean platelet volume and congestive heart failure coexistent with periodontal disease. Pilot studies

Cardiol J. 2019;26(3):253-259. doi: 10.5603/CJ.a2017.0085. Epub 2017 Jul 17.

Abstract

Background: Conducted pilot study concerning mean platelet volume (MPV) parameter among patients suffering from congestive heart failure and periodontal disease.

Methods: Examination of dynamic changes of platelet and periodontal markers in group of 50 patients before and an average of 6 months subsequent to professional periodontal treatment.

Results: Both platelet and periodontal parameters decreased after periodontal treatment, what is more, the decrease of MPV value due to periodontal disease/mm improvement was shown to be statistically significant (p = 0.05).

Conclusions: Improvement of periodontal status may influence decrease of MPV value and increase of congestive heart failure treatment efficacy and effect patient comfort. It is a new, not frequently used pattern of chronic disease treatment optimalization.

Keywords: congestive heart failure; inflammatory response; mean platelet volume; periodontal disease; platelets.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Blood Platelets / metabolism*
  • Female
  • Heart Failure / blood*
  • Heart Failure / complications
  • Heart Failure / diagnosis
  • Heart Failure / therapy
  • Humans
  • Male
  • Mean Platelet Volume*
  • Middle Aged
  • Periodontal Diseases / blood*
  • Periodontal Diseases / complications
  • Periodontal Diseases / diagnosis
  • Periodontal Diseases / therapy
  • Pilot Projects
  • Predictive Value of Tests
  • Prognosis
  • Time Factors