Anatomic and Molecular Imaging in Prostate Cancer

Cold Spring Harb Perspect Med. 2018 Mar 1;8(3):a030619. doi: 10.1101/cshperspect.a030619.

Abstract

Prostate cancer is characterized by a complex set of heterogeneous disease states. This review aims to describe how imaging has been studied within each specific state. As physicians transition into an era of precision medicine, multiparametric magnetic resonance imaging (mpMRI) is proving to be a powerful tool leading the way for a paradigm shift in the diagnosis and management of localized prostate cancer. With further research and development, molecular imaging modalities will likely change the way we approach recurrent and metastatic disease. Given the range of possible oncological progression patterns, a thorough understanding of the underlying carcinogenesis, as it relates to imaging, is a requisite if we are to appropriately manage prostate cancer in future decades.

Publication types

  • Review

MeSH terms

  • Biopsy / methods
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Molecular Imaging / methods*
  • Positron-Emission Tomography
  • Prostatic Neoplasms / diagnostic imaging*
  • Recurrence
  • Tomography, X-Ray Computed