Patent foramen ovale and cryptogenic stroke

Koki Nakanishi; Minoru Yoshiyama; Shunichi Homma

doi:10.1016/j.tcm.2017.06.016

Patent foramen ovale and cryptogenic stroke

Trends Cardiovasc Med. 2017 Nov;27(8):575-581. doi: 10.1016/j.tcm.2017.06.016. Epub 2017 Jul 4.

Authors

Koki Nakanishi¹, Minoru Yoshiyama², Shunichi Homma³

Affiliations

¹ Department of Medicine, Columbia University, New York, NY.
² Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
³ Department of Medicine, Columbia University, New York, NY. Electronic address: sh23@cumc.columbia.edu.

PMID: 28709812
DOI: 10.1016/j.tcm.2017.06.016

Abstract

The presence of a patent foramen ovale (PFO) has been found to be associated with an increased risk of cryptogenic stroke in many case-control studies. This paper reviews the current understanding of the pathophysiology and diagnosis of PFO, and therapeutic options of patients with PFO and cryptogenic stroke.

Keywords: Antithrombotic treatment; Cryptogenic stroke; Echocardiography; Patent foramen ovale.

Publication types

Review

MeSH terms

Echocardiography, Doppler, Color
Echocardiography, Three-Dimensional
Embolism, Paradoxical / complications*
Embolism, Paradoxical / diagnostic imaging
Embolism, Paradoxical / physiopathology
Embolism, Paradoxical / therapy
Foramen Ovale, Patent / complications*
Foramen Ovale, Patent / diagnostic imaging
Foramen Ovale, Patent / physiopathology
Foramen Ovale, Patent / therapy
Humans
Predictive Value of Tests
Prognosis
Recurrence
Risk Assessment
Risk Factors
Stroke / diagnostic imaging
Stroke / etiology*
Stroke / physiopathology
Stroke / prevention & control