Emergence of colistin-resistant Escherichia coli clinical isolates harboring mcr-1 in Vietnam

Tatsuya Tada; Pham Hong Nhung; Kayo Shimada; Mitsuhiro Tsuchiya; Doan Mai Phuong; Nguyen Quoc Anh; Norio Ohmagari; Teruo Kirikae

doi:10.1016/j.ijid.2017.07.003

Emergence of colistin-resistant Escherichia coli clinical isolates harboring mcr-1 in Vietnam

Int J Infect Dis. 2017 Oct:63:72-73. doi: 10.1016/j.ijid.2017.07.003. Epub 2017 Jul 10.

Authors

Tatsuya Tada¹, Pham Hong Nhung², Kayo Shimada³, Mitsuhiro Tsuchiya⁴, Doan Mai Phuong⁵, Nguyen Quoc Anh⁵, Norio Ohmagari⁶, Teruo Kirikae⁷

Affiliations

¹ Department of Microbiology, Juntendo University School of Medicine, Tokyo, Japan; Department of Infectious Diseases, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
² Bach Mai hospital, Hanoi, Vietnam; Department of Microbiology, Hanoi Medical University, Hanoi, Vietnam.
³ Department of Infectious Diseases, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
⁴ Department of Microbiology, Juntendo University School of Medicine, Tokyo, Japan.
⁵ Bach Mai hospital, Hanoi, Vietnam.
⁶ Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
⁷ Department of Microbiology, Juntendo University School of Medicine, Tokyo, Japan; Department of Infectious Diseases, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan. Electronic address: t-kirikae@juntendo.ac.jp.

PMID: 28705756
DOI: 10.1016/j.ijid.2017.07.003

Abstract

The mcr-1 was first detected on a plasmid in colistin-resistant Escherichia coli from livestock and patients in China. We described here the emergence of colistin-resistant E. coli clinical isolates harboring mcr-1 on the chromosomes in Vietnam. To our knowledge, this is the first report of hospital-acquired E. coli isolates harboring mcr-1 in a medical setting in Vietnam.

Keywords: Colistin resistance; Escherichia coli; Vietnam; mcr-1.

MeSH terms

Animals
Anti-Bacterial Agents / pharmacology
China
Colistin / pharmacology*
Cross Infection / epidemiology
Cross Infection / microbiology
Drug Resistance, Multiple, Bacterial*
Escherichia coli / drug effects
Escherichia coli / isolation & purification*
Escherichia coli Infections / epidemiology*
Escherichia coli Infections / veterinary
Escherichia coli Proteins / genetics*
Humans
Livestock / microbiology
Vietnam / epidemiology

Substances

Anti-Bacterial Agents
Escherichia coli Proteins
MCR-1 protein, E coli
Colistin