Myelomonocytic differentiation associated with NPM1-RARA rearrangement

Br J Haematol. 2017 Oct;179(2):183. doi: 10.1111/bjh.14841. Epub 2017 Jul 12.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biopsy
  • Bone Marrow / pathology
  • Bone Marrow Cells / metabolism
  • Bone Marrow Cells / pathology
  • Cell Differentiation / genetics*
  • Child, Preschool
  • Humans
  • Immunophenotyping
  • Leukemia, Myelomonocytic, Acute / diagnosis
  • Leukemia, Myelomonocytic, Acute / drug therapy
  • Leukemia, Myelomonocytic, Acute / genetics*
  • Leukemia, Myelomonocytic, Acute / pathology*
  • Male
  • Neoplasm Grading
  • Nucleophosmin
  • Oncogene Proteins, Fusion / genetics*
  • Oncogene Proteins, Fusion / metabolism
  • Translocation, Genetic*
  • Treatment Outcome

Substances

  • NPM-RARalpha protein, human
  • NPM1 protein, human
  • Oncogene Proteins, Fusion
  • Nucleophosmin