The Electrically Evoked Compound Action Potential: From Laboratory to Clinic

Front Neurosci. 2017 Jun 23:11:339. doi: 10.3389/fnins.2017.00339. eCollection 2017.

Abstract

The electrically evoked compound action potential (eCAP) represents the synchronous firing of a population of electrically stimulated auditory nerve fibers. It can be directly recorded on a surgically exposed nerve trunk in animals or from an intra-cochlear electrode of a cochlear implant. In the past two decades, the eCAP has been widely recorded in both animals and clinical patient populations using different testing paradigms. This paper provides an overview of recording methodologies and response characteristics of the eCAP, as well as its potential applications in research and clinical situations. Relevant studies are reviewed and implications for clinicians are discussed.

Keywords: auditory nerve; clinical application; cochlear implant outcome; electrically evoked compound action potential; stimulating paradigm.

Publication types

  • Review