Diabetic retinopathy (DR) is the leading cause of blindness in the working-age population. Screening for DR is indicated to identify patients with sight-threatening DR (proliferative diabetic retinopathy and diabetic macular oedema) in order to prevent loss of vision. In Denmark, screening is performed by the private-practicing ophthalmologists or in hospital settings. Annual screening intervals are often the standard of care, but longer intervals are preferable for well-controlled patients with no or minimal DR. Automatic screening has the potential to reduce the human burden of grading.