Making HSCs on Demand: Looking Ahead

Cell Stem Cell. 2017 Jul 6;21(1):13. doi: 10.1016/j.stem.2017.06.010.

Abstract

George Daley and Shahin Rafii's groups recently generated multilineage, serially engrafting hematopoietic stem cells (HSCs) from human pluripotent stem cells and endothelial cells, respectively, achieving an important research milestone for the field. We asked some experts in the field to reflect on the broader implications of these findings.

Publication types

  • Review

MeSH terms

  • Animals
  • Endothelial Cells / cytology
  • Endothelial Cells / metabolism*
  • Hematopoietic Stem Cells / cytology
  • Hematopoietic Stem Cells / metabolism*
  • Humans
  • Pluripotent Stem Cells / cytology
  • Pluripotent Stem Cells / metabolism*