Comparative, randomized, double-blind clinical study of alveolar ridge preservation using an extracellular matrix-based dental resorbable membrane in the extraction socket

J Periodontal Implant Sci. 2017 Jun;47(3):165-173. doi: 10.5051/jpis.2017.47.3.165. Epub 2017 Jun 28.

Abstract

Purpose: The aim of this study was to radiographically and clinically compare the effect of extracellular matrix (ECM) membranes on dimensional alterations following a ridge preservation procedure.

Methods: One of 2 different ECM membranes was applied during a ridge preservation procedure. A widely used ECM membrane (WEM; Bio-Gide, Geistlich Biomaterials, Wolhusen, Switzerland) was applied in the treatment group and a newly developed ECM membrane (NEM; Lyso-Gide, Oscotec Inc., Seongnam, Korea) was applied in the control group. Cone-beam computed tomography (CBCT) scans and alginate impressions were obtained 1 week and 6 months after the ridge preservation procedure. Results were analyzed using the independent t-test and the nonparametric Mann-Whitney U test.

Results: There were no significant differences between the ECM membranes in the changes in the dimension, width, and height of the extraction socket or the quantity of bone tissue.

Conclusions: The NEM showed comparable clinical and radiographic results to the WEM following the ridge preservation procedure.

Keywords: Alveolar bone grafting; Bone regeneration; Cone-beam computed tomography; Membranes; Three-dimensional imaging; Tooth socket.