Pulmonary hypertension's variegated landscape: a snapshot

Pulm Circ. 2017 Mar 13;7(1):67-81. doi: 10.1177/2045893216686930. eCollection 2017 Mar.

Abstract

The many types of pulmonary hypertension (PH) are so protean in their biological origin, histological expression, and natural history that it is difficult to create a summary picture of the disease, or to easily compare and contrast characteristics of one type of PH with another. For newcomers to the field, however, such a picture would facilitate a broad understanding of PH. In this paper, we suggest that four characteristics are fundamental to describing the nature of various types of PH, and that taken together they define a number of patterns of PH expression. These characteristics are histopathology, developmental origin, associated clinical conditions, and potential for resolution. The "snapshot" is a way to concisely display the ways that these signal characteristics intersect in select specific types of PH, and is an effort to summarize these patterns in a way that facilitates a "big picture" comprehension of this disease.

Keywords: characteristics; development; pulmonary hypertension (PH); review.

Publication types

  • Review