Generation of a human induced pluripotent stem cell line from urinary cells of a healthy donor using integration free Sendai virus technology

Stem Cell Res. 2017 May:21:167-170. doi: 10.1016/j.scr.2016.09.002. Epub 2016 Sep 13.

Abstract

We have generated a human induced pluripotent stem cell (iPSC) line derived from urinary cells of a 28year old healthy female donor. The cells were reprogrammed using a non-integrating viral vector and have shown full differentiation potential. Together with the iPSC line, the donor provided blood cells for the study of immunological effects of the iPSC line and its derivatives in autologous and allogeneic settings. The line is available and registered in the human pluripotent stem cell registry as BCRTi005-A.

MeSH terms

  • Cell Line
  • Female
  • Humans
  • Induced Pluripotent Stem Cells / cytology
  • Induced Pluripotent Stem Cells / metabolism*
  • Sendai virus*
  • Transduction, Genetic*
  • Urine / cytology*