The indications of tautomeric conversion in amorphous bicalutamide drug

Eur J Pharm Sci. 2017 Dec 15:110:117-123. doi: 10.1016/j.ejps.2017.06.034. Epub 2017 Jun 28.
No abstract available

Keywords: Amorphous bicalutamide; DFT calculation; Dielectric spectroscopy; Proton transfer reaction; Tautomerization.

MeSH terms

  • Anilides / chemistry*
  • Dielectric Spectroscopy / methods
  • Humans
  • Isomerism
  • Magnetic Resonance Spectroscopy / methods
  • Models, Molecular
  • Molecular Structure
  • Nitriles / chemistry*
  • Spectroscopy, Fourier Transform Infrared / methods
  • Thermodynamics
  • Tosyl Compounds / chemistry*

Substances

  • Anilides
  • Nitriles
  • Tosyl Compounds
  • bicalutamide