Nontuberculous mycobacterial disease in childhood - update on diagnostic approaches and treatment

J Infect. 2017 Jun:74 Suppl 1:S136-S142. doi: 10.1016/S0163-4453(17)30204-9.

Abstract

Recent studies suggest that the incidence of nontuberculous mycobacterial infections in children may be increasing. Nontuberculous mycobacterial lymphadenitis, skin and soft tissue infection, and pulmonary disease each present unique challenges in relation to diagnosis and treatment. In this update, we critically review the recent literature on the epidemiology, clinical features, diagnostic approaches and treatment of nontuberculous mycobacterial disease in children. In addition, we outline key areas warranting further research.

Keywords: Atypical; Diagnosis; Epidemiology; Lymphadenitis; Mycobacteria; Non-tuberculous; Treatment.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / therapeutic use*
  • Child
  • Child, Preschool
  • Diagnostic Tests, Routine / methods*
  • Disease Management*
  • Humans
  • Infant
  • Infant, Newborn
  • Mycobacterium Infections, Nontuberculous / diagnosis*
  • Mycobacterium Infections, Nontuberculous / drug therapy*
  • Mycobacterium Infections, Nontuberculous / epidemiology
  • Mycobacterium Infections, Nontuberculous / pathology
  • Nontuberculous Mycobacteria / isolation & purification*

Substances

  • Anti-Bacterial Agents