[Quantitative Imaging Assessment of Tumor Response to Chemoradiation in Lung Cancer]

Zhongguo Fei Ai Za Zhi. 2017 Jun 20;20(6):407-414. doi: 10.3779/j.issn.1009-3419.2017.06.07.
[Article in Chinese]

Abstract

Precision medicine demands accurate assessment of tumor response to therapies with the purpose of timely optimization or adjustment of the given treatment regimens. Chemoradiation remains the standard of care in advanced lung cancers and imaging-based noninvasive response evaluation could improve therapeutic efficacy and reduce treatment-related severe side effects. In this review, we overviewed the applications and pitfalls of major imaging modalities in response evaluation in lung cancer from a quantitative perspective. The development of radiomics will provide more precise information for treatment predicting, evaluation and prognosis.

精准医疗的实施要求及时准确地对治疗疗效进行评估,以便于治疗方案的调整和优化,从而进一步提高疗效,改善预后。以定量评估为基础的影像组学以其无创、直观和可重复的特点在临床疗效评估方面具有不可替代的作用。本文将综述定量影像学在肺癌放化疗疗效评估中的应用现状及其相关进展。.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / administration & dosage
  • Chemoradiotherapy
  • Diagnostic Imaging / methods*
  • Humans
  • Lung Neoplasms / diagnostic imaging*
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / radiotherapy
  • Radiopharmaceuticals / administration & dosage

Substances

  • Antineoplastic Agents
  • Radiopharmaceuticals

Grants and funding

本文受国家自然科学基金(No.81472794)、上海市科学技术委员会基金(No.124119a0400)资助