Background: Up to 8% of women in their reproductive years are affected by Premenstral Dysphoric Disorder (PMDD). Sleep disturbances such as insomnia or hypersomnia are one of the DSM-IV-TR's defining criteria for the diagnosis of PMDD and are found in about 70% of women with the disorder. However, studies are lacking that specifically address the effects of PMDD on quality of sleep.
Aim: This study was designed to evaluate the prevalence of Premenstrual DysphoricDisorder (PMDD) and its impact on sleep quality in female university students.
Methods: We developed an 18-item PMDD scale based on The Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) to diagnose PMDD in female university studentswho ranged in age from 18 to 30 years and had regular menstrual cycles.Participants were categorized into a PMDD group or a No/PMDD group and sleep quality was compared between the two groups. The evaluation tool used to measure sleep quality was the Pittsburgh Sleep Quality Index (PSQI).
Results: The prevalence of PMDD in female universitystudents was 25.5%. Analysis of the PSQI demonstrated that 80.5% of those in PMDD group had a PSQI that scored >5; however, only 56.4% in the No/PMDD grouphad a PSQI that scored >5 (χ2 =12.459, p<0.001). The mean PSQI score was 8.2(3.4) in the PMDD group and was 6.5(3.1) in the No/PMDD group (t=3.648, p<0.001).
Conclusions: Female university students who experience PMDD are deeply affected by sleep problems. Lower sleep quality, daytime dysfunction, and sleep disturbance are common sleep problems among female university students with PMDD.
背景: 高达8% 的育龄妇女受经前期烦躁障碍（PMDD） 所困。DSM-IV-TR 把失眠或嗜睡等睡眠紊乱作为PMDD 的诊断标准之一。大约70% 的PMDD 患者存在睡眠紊 乱。然而，专注解决PMDD 对睡眠质量影响的有关研 究却非常缺乏。.
目标: 本研究旨在评估女大学生中PMDD 的患病率及 其对睡眠质量的影响。.
方法: 我们根据精神障碍诊断与统计手册第四版修订 版(DSM-IV-TR) 开发了PMDD 量表（18 项）。对月经 周期规律、年龄在18~30 岁的女大学生，用上述量表 诊断PMDD。把研究对象分为PMDD 组或非PMDD 组， 比较两组的睡眠质量。用匹兹堡睡眠质量指数（PSQI） 评估睡眠质量。.
结果: 女大学生PMDD 的患病率为25.5%。PSQI 分析 表明PMDD 组中80.5% 的女大学生PSQI 得分＞ 5， 而非 PMDD 组中相应的比例只有56.4%（χ2=12.459, p<0.001）。PMDD 组PSQI 平均分（标准差）为8.2 (3.4) 而非PMDD 组为6.5 (3.1)（t=3.648, p<0.001）。.
结论: 患有 PMDD 的女大学生睡眠问题严重。睡眠质 量差、日间功能障碍以及睡眠紊乱是患PMDD 的女大 学生中常见的睡眠问题。.
关键词: 经前期烦躁障碍；睡眠质量；匹兹堡睡眠质 量指数；女大学生.
Keywords: Pittsburgh Sleep Quality Index; Premenstrual Dysphoric Disorder; Sleep quality; female university students.