Beyond the wall: can D-amino acids and small molecule inhibitors eliminate infections?

Ilana Kolodkin-Gal

doi:10.4155/fmc-2017-0069

Beyond the wall: can D-amino acids and small molecule inhibitors eliminate infections?

Future Med Chem. 2017 Jun;9(9):843-846. doi: 10.4155/fmc-2017-0069. Epub 2017 Jun 21.

Author

Ilana Kolodkin-Gal¹

Affiliation

¹ Department of Molecular Genetics, Weizmann Institute of Science, 234 Herzl Street, Rehovot 76100, Israel.

PMID: 28635317
DOI: 10.4155/fmc-2017-0069

No abstract available

Keywords: D-amino acids; antibiofilm therapy; antibiotic resistance; biofilms; biofouling; cell–wall; dispersal; extracellular matrix; persistent infections; translation.

Publication types

Editorial

MeSH terms

Amino Acids / chemistry*
Amino Acids / therapeutic use*
Bacterial Infections / drug therapy*
Bacterial Infections / microbiology
Bacterial Infections / pathology
Biofilms / drug effects
Cell Wall / drug effects
Gram-Negative Bacteria / drug effects
Gram-Negative Bacteria / physiology
Gram-Positive Bacteria / drug effects
Gram-Positive Bacteria / physiology
Humans
Small Molecule Libraries / chemistry
Small Molecule Libraries / pharmacology
Small Molecule Libraries / therapeutic use*

Substances

Amino Acids
Small Molecule Libraries