Ceftazidime-Avibactam and Aztreonam, an Interesting Strategy To Overcome β-Lactam Resistance Conferred by Metallo-β-Lactamases in Enterobacteriaceae and Pseudomonas aeruginosa

Antimicrob Agents Chemother. 2017 Aug 24;61(9):e01008-17. doi: 10.1128/AAC.01008-17. Print 2017 Sep.
No abstract available

Keywords: avibactam; aztreonam; ceftazidime.

Publication types

  • Letter

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use*
  • Azabicyclo Compounds / therapeutic use*
  • Aztreonam / therapeutic use*
  • Bacteremia / drug therapy
  • Bacteremia / microbiology
  • Catheter-Related Infections / drug therapy
  • Catheter-Related Infections / microbiology
  • Ceftazidime / therapeutic use*
  • Drug Combinations
  • Enterobacteriaceae / drug effects*
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Pneumonia / drug therapy
  • Pneumonia / microbiology
  • Pseudomonas aeruginosa / drug effects*
  • Thrombophlebitis / drug therapy
  • Thrombophlebitis / microbiology
  • beta-Lactam Resistance / genetics
  • beta-Lactamase Inhibitors / therapeutic use*
  • beta-Lactamases / genetics

Substances

  • Anti-Bacterial Agents
  • Azabicyclo Compounds
  • Drug Combinations
  • avibactam, ceftazidime drug combination
  • beta-Lactamase Inhibitors
  • Ceftazidime
  • beta-Lactamases
  • Aztreonam