Comparison between Bilistick System and transcutaneous bilirubin in assessing total bilirubin serum concentration in jaundiced newborns

J Perinatol. 2017 Sep;37(9):1028-1031. doi: 10.1038/jp.2017.94. Epub 2017 Jun 15.

Abstract

Objective: To compare the performance and accuracy of the JM-103 transcutaneous bilirubinometer and Bilistick System in measuring total serum bilirubin for the early identification of neonatal hyperbilirubinemia.

Study design: The study was performed on 126 consecutive term and near-term (⩾36 weeks' gestational age) jaundiced newborns in Cairo University Children Hospital NICU, Egypt. Total serum bilirubin was assayed concurrently by the clinical laboratory and Bilistick System and estimated using the JM-103 transcutaneous bilirubin instrument. Bland-Altman analysis was used to evaluate the agreement between determinations.

Result: The limits of agreement of the Bilistick System (-5.8 to 3.3 mg dl-1) and JM-103 system (-5.4 to 6.0 mg dl-1) versus the clinical laboratory results were similar.

Conclusion: The Bilistick System is an accurate alternative to transcutaneous (TcB) determination for early diagnosis and proper management of the neonatal jaundice.

Publication types

  • Comparative Study

MeSH terms

  • Bilirubin / blood*
  • Biomarkers / blood
  • Egypt
  • Female
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Jaundice, Neonatal / blood*
  • Jaundice, Neonatal / diagnosis
  • Male
  • Neonatal Screening / methods*

Substances

  • Biomarkers
  • Bilirubin