Biomarkers of Renal Function: Towards Clinical Actionability

Clin Pharmacol Ther. 2017 Sep;102(3):481-492. doi: 10.1002/cpt.765. Epub 2017 Jul 21.

Abstract

This review provides an overview of the clinical value of the most relevant renal biomarkers, focusing on two main clinical conditions: acute kidney injury and chronic kidney disease. We categorize biomarkers according to their actionability, in terms of a documented response to treatment in relation to outcomes. Furthermore, we introduce a new category of renal biomarkers, metabolic biomarkers, and underscore their capacity to be highly actionable.

Publication types

  • Review

MeSH terms

  • Acute Kidney Injury / physiopathology*
  • Biomarkers / metabolism*
  • Humans
  • Kidney / metabolism
  • Kidney / physiopathology
  • Kidney Function Tests
  • Renal Insufficiency, Chronic / physiopathology*

Substances

  • Biomarkers