In the last decades, marine natural products (MNPs), have attracted extensive interest from both chemists and pharmacologists due to their chemical and bioactive diversities. This special issue, collecting total synthesis and structural modification of six different type of bioactive MNPs, is expected to inspire and attract more research effects invested into MNP research.
Keywords: antitumor activity; enzyme-inhibitory activity; marine natural products; neuroprotective activity; structural modification; total synthesis.