Abstract
Photodriven DNA strand displacement by using a 2',6'-dimethylazobenzene-tethered strand and poly(l-lysine)-graft-dextran (PLL-g-Dex) as a chaperone is reported. Rapid strand displacement was reversibly induced by UV and visible-light irradiation without any toehold portion. To further improve the method, the concentration of PLL-g-Dex and the number of equivalents of the photoresponsive strand were optimised. Optimally, 64 % strand displacement was reversibly induced by alternating UV and visible-light irradiation.
Keywords:
DNA; nanotechnology; photochemistry; polymers; substituent effects.
© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Azo Compounds / chemistry
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Azo Compounds / radiation effects*
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DNA / chemistry
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DNA / radiation effects*
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Dextrans / chemistry*
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Fluoresceins / chemistry
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Fluorescent Dyes / chemistry
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Isomerism
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Nanotechnology
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Nucleic Acid Hybridization
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Polylysine / analogs & derivatives*
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Polylysine / chemistry
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Transition Temperature
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Ultraviolet Rays
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p-Dimethylaminoazobenzene / analogs & derivatives
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p-Dimethylaminoazobenzene / chemistry
Substances
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Azo Compounds
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Dextrans
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Fluoresceins
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Fluorescent Dyes
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poly(lysine)-graft-dextran
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Polylysine
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4-(4-dimethylaminophenylazo)benzoic acid
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4-carboxyfluorescein
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DNA
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p-Dimethylaminoazobenzene