Objectives: Patients with advanced cancer often suffer from severe malnutrition and gastrointestinal obstruction. This population could benefit from home parenteral nutrition (HPN). The aim of this study was to observe the outcome of patients with advanced cancer patients who were eligible for HPN.
Methods: All patients in the nutrition clinic who received HPN over the past 7 y were included in the present study. We compared patients with advanced cancer with the noncancer population in terms of hospitalization rate and mortality.
Results: Of 221 advanced cancer patients, 153 who had no oral/enteral intake and who received HPN survived. Of these, 35% survived for 6 mo, 27% for 1 y, 18.9% survived 2 y, and 3.9% survived for the 7 y of the follow-up. Hospitalization rate was not significantly different from the noncancer population.
Conclusion: These results show that HPN is a relevant palliative therapy for patients with advanced cancer patients without oral or enteral feeding access.
Keywords: Advanced cancer; Gastrointestinal obstruction; Home parenteral nutrition; Karnofsky scale score; Palliative care.
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