Heart failure: BRD4 inhibition slows HF progression

Nat Rev Cardiol. 2017 Jul;14(7):382-383. doi: 10.1038/nrcardio.2017.86. Epub 2017 Jun 1.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Azepines / therapeutic use*
  • Cell Cycle Proteins
  • Disease Progression
  • Heart Failure / drug therapy*
  • Heart Failure / metabolism
  • Humans
  • Nuclear Proteins / antagonists & inhibitors*
  • Transcription Factors / antagonists & inhibitors*
  • Triazoles / therapeutic use*

Substances

  • (+)-JQ1 compound
  • Azepines
  • BRD4 protein, human
  • Cell Cycle Proteins
  • Nuclear Proteins
  • Transcription Factors
  • Triazoles