Point-of-Care Testing for Infectious Diseases: Past, Present, and Future

J Clin Microbiol. 2017 Aug;55(8):2313-2320. doi: 10.1128/JCM.00476-17. Epub 2017 May 24.

Abstract

Point-of-care (POC) diagnostics provide rapid actionable information for patient care at the time and site of an encounter with the health care system. The usual platform has been the lateral flow immunoassay. Recently, emerging molecular diagnostics have met requirements for speed, low cost, and ease of use for POC applications. A major driver for POC development is the ability to diagnose infectious diseases at sites with a limited infrastructure. The potential use in both wealthy and resource-limited settings has fueled an intense effort to build on existing technologies and to generate new technologies for the diagnosis of a broad spectrum of infectious diseases.

Keywords: infectious disease; lateral flow immunoassay; molecular diagnostic; point-of-care; rapid tests.

Publication types

  • Review

MeSH terms

  • Chromatography, Affinity / methods
  • Chromatography, Affinity / statistics & numerical data
  • Chromatography, Affinity / trends
  • Communicable Diseases / diagnosis*
  • Humans
  • Molecular Diagnostic Techniques / methods
  • Molecular Diagnostic Techniques / statistics & numerical data
  • Molecular Diagnostic Techniques / trends
  • Point-of-Care Testing / statistics & numerical data*
  • Point-of-Care Testing / trends*