Hospital Outbreaks of Middle East Respiratory Syndrome, Daejeon, South Korea, 2015

Emerg Infect Dis. 2017 Jun;23(6):898-905. doi: 10.3201/eid2306.160120.

Abstract

From May through July 2015, a total of 26 cases of Middle East Respiratory Syndrome were reported from 2 hospitals in Daejeon, South Korea, including 1 index case and 25 new cases. We examined the epidemiologic features of these cases and found an estimated median incubation period of 6.1 days (8.8 days in hospital A and 4.6 days in hospital B). The overall attack rate was 3.7% (4.7% in hospital A and 3.0% in hospital B), and the attack rates among inpatients and caregivers in the same ward were 12.3% and 22.5%, respectively. The overall case-fatality rate was 44.0% (28.6% in hospital A and 63.6% in hospital B). The use of cohort quarantine may have played a role in preventing community spread, but additional transmission occurred among members of the hospital cohort quarantined together. Caregivers may have contributed in part to the transmission.

Keywords: MERS; Middle East respiratory syndrome; South Korea; hospital-acquired condition; outbreaks; viruses; zoonoses.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Coronavirus Infections / epidemiology*
  • Coronavirus Infections / pathology
  • Coronavirus Infections / transmission*
  • Coronavirus Infections / virology
  • Disease Outbreaks
  • Female
  • Hospitals*
  • Humans
  • Male
  • Middle Aged
  • Quarantine
  • Republic of Korea / epidemiology