Functionalization of P4 through Direct P-C Bond Formation

Jaap E Borger; Andreas W Ehlers; J Chris Slootweg; Koop Lammertsma

doi:10.1002/chem.201702067

Functionalization of P₄ through Direct P-C Bond Formation

Chemistry. 2017 Sep 4;23(49):11738-11746. doi: 10.1002/chem.201702067. Epub 2017 Jul 27.

Authors

Jaap E Borger¹, Andreas W Ehlers^{1

2

3}, J Chris Slootweg^{1

3}, Koop Lammertsma^{1

2}

Affiliations

¹ Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1083, 1081 HV, Amsterdam, the Netherlands.
² Department of Chemistry, University of Johannesburg, Auckland Park, Johannesburg, 2006, South Africa.
³ Current address: Van "t Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, the Netherlands.

Abstract

Research on chlorine-free conversions of P₄ into organophosphorus compounds (OPCs) has a long track record, but methods that allow desirable, direct P-C bond formations have only recently emerged. These include the use of metal organyls, carbenes, carboradicals, and photochemical approaches. The versatile product scope enables the preparation of both industrially relevant organophosphorus compounds, as well as a broad range of intriguing new compound classes. Herein we provide a concise overview of recent breakthroughs and outline the acquired fundamental insights to aid future developments.

Keywords: main group chemistry; nucleophilic addition; organophosphorus compounds; phosphorus; phosphorus anions.

Publication types

Review