[State III large cell carcinoma of the lung cured by radiotherapy--a case report]

Gan No Rinsho. 1988 Nov;34(14):1985-9.
[Article in Japanese]

Abstract

Presented is the case of a 61-year-old male whose chief complaints were hoarseness, cough, and bloody sputum. Chest radiography demonstrated a left hilar mass with mediastinal widening, a peripheral localized infiltrate and the elevation of the left hemidiaphragm. By means of a mediastinoscopy, a biopsy was done on the enlarged mediastinal lymph node and a histological diagnosis of a large cell carcinoma was confirmed. He was graded as in Stage III (T2N2M0) and was placed under radiotherapy with 60Co. Complete response was obtained after a total dose of 6150 cGy. Following this radiotherapy, he was given multiple courses of mild chemotherapy and the disease as of this report has been under control for 7 years. This case may be unusual, but suggests the possibility of a cure of lung cancer by irradiation under certain conditions.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Carcinoma, Small Cell / drug therapy
  • Carcinoma, Small Cell / pathology
  • Carcinoma, Small Cell / radiotherapy*
  • Cyclophosphamide / administration & dosage
  • Cytarabine / administration & dosage
  • Doxorubicin / administration & dosage
  • Fluorouracil / administration & dosage
  • Humans
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / pathology
  • Lung Neoplasms / radiotherapy*
  • Male
  • Middle Aged
  • Mitomycin
  • Mitomycins / administration & dosage
  • Prognosis
  • Radiotherapy Dosage
  • Vincristine / administration & dosage

Substances

  • Mitomycins
  • Cytarabine
  • Mitomycin
  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Fluorouracil

Supplementary concepts

  • MFC protocol