Pacing Discovery: G-Protein β Subunit Mutations in Sinus Node Dysfunction

Circ Res. 2017 May 12;120(10):1524-1526. doi: 10.1161/CIRCRESAHA.117.310953.

Authors

Elisabeth M Lodder¹, Arie O Verkerk¹, Connie R Bezzina²

Affiliations

¹ From the Heart Center, Department of Clinical and Experimental Cardiology (E.M.L., A.O.V., C.R.B.) and Department of Medical Biology (A.O.V.), Academic Medical Center, Amsterdam, the Netherlands.
² From the Heart Center, Department of Clinical and Experimental Cardiology (E.M.L., A.O.V., C.R.B.) and Department of Medical Biology (A.O.V.), Academic Medical Center, Amsterdam, the Netherlands. c.r.bezzina@amc.uva.nl.

PMID: 28495981
DOI: 10.1161/CIRCRESAHA.117.310953

No abstract available

Keywords: Editorials; acetylcholine; cell membrane; genetic variation; heart rate; mutation.

Publication types

Editorial
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Cardiac Pacing, Artificial
GTP-Binding Protein beta Subunits*
GTP-Binding Proteins
Humans
Mutation
Sick Sinus Syndrome
Sinoatrial Node*

Substances

GNB2 protein, human
GTP-Binding Protein beta Subunits
GTP-Binding Proteins