Novel cosmetic formulations containing a biosurfactant from Lactobacillus paracasei

Colloids Surf B Biointerfaces. 2017 Jul 1:155:522-529. doi: 10.1016/j.colsurfb.2017.04.026. Epub 2017 Apr 20.

Abstract

Cosmetic and personal care products including toothpaste, shampoo, creams, makeup, among others, are usually formulated with petroleum-based surfactants, although in the last years the consume trend for "green" products is inducing the replacement of surface-active agents in these formulations by natural surfactants, so-called biosurfactants. In addition to their surfactant capacity, many biosurfactants can act as good emulsifiers, which is an extra advantage in the preparation of green cosmetic products. In this work, a biosurfactant obtained from Lactobacillus paracasei was used as a stabilizing agent in oil-in-water emulsions containing essential oils and natural antioxidant extract. In the presence of biosurfactant, maximum percentages of emulsion volumes (EV=100%) were observed, with droplets sizes about 199nm. These results were comparable with the ones obtained using sodium dodecyl sulfate (SDS), a synthetic well known surfactant with high emulsify capacity. Moreover, the biosurfactant and emulsions cytotoxicity was evaluated using a mouse fibroblast cell line. Solutions containing 5g/L of biosurfactant presented cell proliferation values of 97%, whereas 0.5g/L of SDS showed a strong inhibitory effect. Overall, the results herein gathered are very promising towards the development of new green cosmetic formulations.

Keywords: Antioxidants; Biosurfactant; Cells; Emulsions; Essential oils; Skin.

MeSH terms

  • 3T3 Cells
  • Animals
  • Antioxidants / chemistry
  • Biological Products / chemistry*
  • Cell Proliferation / drug effects
  • Cell Survival / drug effects
  • Cosmetics / chemistry*
  • Emulsifying Agents / chemistry
  • Emulsifying Agents / pharmacology
  • Emulsions / chemistry
  • Emulsions / pharmacology
  • Lacticaseibacillus paracasei / chemistry*
  • Mice
  • Oils, Volatile / chemistry
  • Sodium Dodecyl Sulfate / chemistry
  • Sodium Dodecyl Sulfate / pharmacology
  • Surface-Active Agents / chemistry*

Substances

  • Antioxidants
  • Biological Products
  • Cosmetics
  • Emulsifying Agents
  • Emulsions
  • Oils, Volatile
  • Surface-Active Agents
  • Sodium Dodecyl Sulfate