Haemodynamic findings in obstructive hypertrophic cardiomyopathy: pulsus bisferiens and Brockenbrough-Braunwald-Morrow sign

J Cardiovasc Med (Hagerstown). 2016 Dec:17 Suppl 2:e154-e155. doi: 10.2459/JCM.0000000000000067.

Abstract

: A 55-year-old gentleman with hypertrophic obstructive cardiomyopathy and heart failure symptoms underwent cardiac catheterization, which confirmed a significant pressure drop (60 mmHg) across the left ventricular outflow tract, a double-peaked pulse (pulsus bisferiens) and an absent postextrasystolic potentiation (Brockenbrough-Braunwald-Morrow sign) in the left ventricular outflow tract and the aorta. He was treated with medical therapy optimization and intracardiac defibrillator implantation. Cardiac catheterization may provide characteristic clues not only to diagnose obstructive hypertrophic cardiomyopathy, but also to understand its pathophysiological correlates.

Publication types

  • Case Reports

MeSH terms

  • Arrhythmias, Cardiac / diagnosis
  • Arrhythmias, Cardiac / etiology
  • Cardiac Catheterization*
  • Cardiomyopathy, Hypertrophic / complications
  • Cardiomyopathy, Hypertrophic / diagnosis*
  • Cardiomyopathy, Hypertrophic / physiopathology
  • Cardiomyopathy, Hypertrophic / therapy
  • Cardiovascular Agents / therapeutic use
  • Defibrillators, Implantable
  • Echocardiography
  • Electric Countershock / instrumentation
  • Electrocardiography
  • Hemodynamics*
  • Humans
  • Male
  • Middle Aged
  • Mitral Valve Insufficiency / diagnosis
  • Mitral Valve Insufficiency / etiology
  • Predictive Value of Tests
  • Treatment Outcome
  • Ventricular Function, Left
  • Ventricular Outflow Obstruction / diagnosis
  • Ventricular Outflow Obstruction / etiology
  • Ventricular Pressure

Substances

  • Cardiovascular Agents