Circulating tumor cells and coagulation-Minireview

Branislav Bystricky; James M Reuben; Michal Mego

doi:10.1016/j.critrevonc.2017.04.003

Circulating tumor cells and coagulation-Minireview

Crit Rev Oncol Hematol. 2017 Jun:114:33-42. doi: 10.1016/j.critrevonc.2017.04.003. Epub 2017 Apr 6.

Authors

Branislav Bystricky¹, James M Reuben², Michal Mego³

Affiliations

¹ 2(nd) Department of Medical Oncology, Faculty of Medicine, Comenius University and National Cancer Institute, Bratislava, Slovakia; Department of Oncology, Trencin Hospital, Trencin, Slovakia.
² Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
³ 2(nd) Department of Medical Oncology, Faculty of Medicine, Comenius University and National Cancer Institute, Bratislava, Slovakia. Electronic address: misomego@gmail.com.

PMID: 28477745
DOI: 10.1016/j.critrevonc.2017.04.003

Abstract

Venous thromboembolic events in cancer patients signify poor prognosis. Prophylactic treatment of ambulatory patients with anticoagulants is currently not recommended. Circulating tumor cells, either directly or indirectly, are associated with prothrombotic state. In this review, we discuss various interactions of circulating tumor cells with the coagulation pathway in cancer patient.

Keywords: Cancer; Circulating tumor cells; Coagulation; Venous thromboembolic events.

Publication types

Review

MeSH terms

Animals
Blood Coagulation*
Humans
Neoplastic Cells, Circulating / pathology*
Venous Thromboembolism / blood
Venous Thromboembolism / physiopathology*