p.Y317H is a new JAK2 gain-of-function mutation affecting the FERM domain in a myelofibrosis patient with CALR mutation

Haematologica. 2017 Aug;102(8):e328-e331. doi: 10.3324/haematol.2017.166439. Epub 2017 May 4.

Authors

Laura Eder-Azanza^{1

2}, Cristina Hurtado^{1

2}, David Navarro-Herrera¹, Paula Aranaz¹, Francisco J Novo^{1

2}, José L Vizmanos^{3

2}

Affiliations

¹ University of Navarra, School of Sciences. Department of Biochemistry & Genetics, Pamplona.
² Navarra Institute for Health Research (IdiSNA), Pamplona, Spain.
³ University of Navarra, School of Sciences. Department of Biochemistry & Genetics, Pamplona jlvizmanos@unav.es.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Calreticulin / genetics*
Cell Line
FERM Domains / genetics*
Gain of Function Mutation*
Humans
Janus Kinase 2 / genetics*
Primary Myelofibrosis / genetics*
Signal Transduction / genetics

Substances

Calreticulin
JAK2 protein, human
Janus Kinase 2