Thrombolysis of prosthetic mitral valve thrombosis in an infant

J Card Surg. 2017 May;32(5):310-312. doi: 10.1111/jocs.13135.

Abstract

A 7-week-old female developed thrombosis of a mechanical mitral valve and was successfully treated with recombinant tissue plasminogen activator (rt-PA). The management of infants with thrombosed mechanical prosthesis is reviewed.

Publication types

  • Case Reports

MeSH terms

  • Aspirin
  • Coronary Vessels / injuries
  • Female
  • Fibrinolytic Agents / administration & dosage*
  • Heart Septal Defects, Ventricular / complications
  • Heart Septal Defects, Ventricular / surgery
  • Heart Valve Prosthesis Implantation / adverse effects*
  • Heart Valve Prosthesis Implantation / methods*
  • Heart Valve Prosthesis* / adverse effects
  • Humans
  • Infant
  • Injections, Intralesional
  • Mitral Valve / surgery*
  • Mitral Valve Insufficiency / complications
  • Mitral Valve Insufficiency / surgery*
  • Postoperative Complications / etiology
  • Prosthesis Failure
  • Recombinant Proteins / administration & dosage
  • Reoperation
  • Thrombolytic Therapy / methods*
  • Thrombosis / drug therapy*
  • Thrombosis / etiology*
  • Tissue Plasminogen Activator / administration & dosage*
  • Treatment Outcome
  • Ventricular Dysfunction, Left / etiology

Substances

  • Fibrinolytic Agents
  • Recombinant Proteins
  • Tissue Plasminogen Activator
  • Aspirin