Silicon-substituted Xanthene Dyes and Their Unique Photophysical Properties for Fluorescent Probes

Takayuki Ikeno; Tetsuo Nagano; Kenjiro Hanaoka

doi:10.1002/asia.201700385

Silicon-substituted Xanthene Dyes and Their Unique Photophysical Properties for Fluorescent Probes

Chem Asian J. 2017 Jul 4;12(13):1435-1446. doi: 10.1002/asia.201700385. Epub 2017 Jun 5.

Authors

Takayuki Ikeno¹, Tetsuo Nagano², Kenjiro Hanaoka¹

Affiliations

¹ Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
² Drug Discovery Initiative, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

PMID: 28452155
DOI: 10.1002/asia.201700385

Abstract

Silicon-substituted xanthene dyes, with Si in place of the O atom at the xanthene 10-position, are practically useful as far-red to near-infrared fluorophores. Many fluorescent probes based on them have recently been reported. These fluorophores retain the advantages of typical xanthene dyes and also show unique properties suitable for applications such as multi-color and super-resolution imaging.

Keywords: fluorescence; fluorescence spectroscopy; fluorescent dyes; fluorescent probes; sensors.

Publication types

Review

MeSH terms

Fluorescent Dyes / chemistry*
Molecular Structure
Photochemical Processes
Silicon / chemistry*
Xanthenes / chemistry*

Substances

Fluorescent Dyes
Xanthenes
Silicon