MYRFs on the Move to Rewire Circuits

Colleen N McLaughlin; Heather T Broihier

doi:10.1016/j.devcel.2017.04.008

MYRFs on the Move to Rewire Circuits

Dev Cell. 2017 Apr 24;41(2):123-124. doi: 10.1016/j.devcel.2017.04.008.

Authors

Colleen N McLaughlin¹, Heather T Broihier²

Affiliations

¹ Department of Neurosciences, Case Western Reserve University, Cleveland, OH 44106, USA.
² Department of Neurosciences, Case Western Reserve University, Cleveland, OH 44106, USA. Electronic address: heather.broihier@case.edu.

PMID: 28441525
DOI: 10.1016/j.devcel.2017.04.008

Abstract

Synaptic plasticity occurs in response to intrinsic and extrinsic cues and is a key step in the formation of mature neuronal circuits. In this issue of Developmental Cell, Meng et al. (2017) find that two conserved Myrf transcription factors coexist in the same complex to promote developmental circuit remodeling.

Publication types

Review
Comment

MeSH terms

Animals
Humans
Membrane Proteins / metabolism*
Nerve Net / physiology
Neurogenesis / physiology*
Neuronal Plasticity / physiology*
Neurons / physiology*
Synapses / physiology*
Transcription Factors / metabolism*

Substances

Membrane Proteins
Myrf protein, human
Transcription Factors