Novel bioprinting method using a pectin based bioink

Technol Health Care. 2017 Aug 9;25(4):651-655. doi: 10.3233/THC-160764.

Abstract

One major challenge of bioprinting is to develop a viable bioink to act as an extracellular matrix. This study investigated a novel method for bioprinting using a pectin based bioink. Besides pectin, Pluronic® F-127 was incorporated into the bioink to obtain the desired shape during the initial bioprinting process at 37∘C. Once an object was printed it was treated with Ca2+ (pectin cross-linker) to create the final tissue/organ structure. The results indicated that pectin/Pluronic® F-127 is a potential bioink. Moreover, this methodology provides a novel and fast approach for bioprinting.

Keywords: Bioprinting; bioink; hydrogel; pectin; scaffolds.

MeSH terms

  • Bioprinting / methods*
  • Calcium / chemistry
  • Cations, Divalent
  • Extracellular Matrix*
  • Humans
  • Pectins / chemistry*
  • Poloxamer / chemistry
  • Tissue Scaffolds*

Substances

  • Cations, Divalent
  • Poloxamer
  • Pectins
  • Calcium