Uveitis in Siriraj Hospital: pattern differences between immune-related uveitis and infectious uveitis in a university-based tertiary care hospital

Int Ophthalmol. 2018 Apr;38(2):673-678. doi: 10.1007/s10792-017-0515-5. Epub 2017 Apr 20.

Abstract

Purpose: To describe a proportion of uveitis and to analyse differences between immune-related uveitis and infectious uveitis groups.

Methods: A retrospective study of 458 uveitis patients were categorized into immune-related uveitis, infectious uveitis, masquerade, and undetermined groups. The pattern of inflammation was described. Subgroup analysis was performed to compare pattern differences between immune-related uveitis and infectious uveitis groups.

Results: The most common location of inflammation was the anterior eye segment. Vogt-Koyanagi-Harada disease was the most common identifiable cause. From multivariate analysis, variables found to be significantly different between immune-related uveitis group and infectious uveitis group were age of onset, presence of systemic autoimmune diseases, HIV infection, and laterality.

Conclusions: Idiopathic anterior uveitis was the most prevalent diagnosis. Vogt-Koyanagi-Harada disease was the most common identifiable uveitis. Most immune-related uveitis patients were young and presented with chronic bilateral panuveitis, with most patients in the infectious uveitis group presenting with chronic unilateral posterior uveitis.

Keywords: Epidemiology; Immune; Infection; Proportion; Uveitis.

MeSH terms

  • Adult
  • Cross-Sectional Studies
  • Eye Infections / epidemiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Prevalence
  • Retrospective Studies
  • Tertiary Care Centers / statistics & numerical data
  • Thailand / epidemiology
  • Uveitis / epidemiology*
  • Uveitis, Anterior / epidemiology
  • Uveomeningoencephalitic Syndrome / epidemiology