[Treatment of anaphylactic schock in pregnant women]

Ugeskr Laeger. 2017 Apr 10;179(15):V11160786.
[Article in Danish]

Abstract

This is an update on the treatment of anaphylactic shock in pregnant women. Most guidelines recommend adrenaline as first-line treatment in all patients, but in pregnant patients some recommend ephedrine due to a potential risk of utero-placental hypoperfusion with adrenaline. However, ephedrine is a less potent vasopressor than adrenaline and does not possess the same anti-inflammatory or broncho-dilating effects. As immediate and correct treatment is essential for both the maternal and the fetal outcome, adrenaline should be first-line treatment also in pregnant women.

Publication types

  • Review

MeSH terms

  • Algorithms
  • Anaphylaxis / diagnosis
  • Anaphylaxis / drug therapy*
  • Diagnosis, Differential
  • Ephedrine / pharmacology
  • Ephedrine / therapeutic use*
  • Epinephrine / adverse effects
  • Epinephrine / pharmacology
  • Epinephrine / therapeutic use*
  • Female
  • Humans
  • Placenta / blood supply
  • Pregnancy
  • Pregnancy Complications / drug therapy*
  • Risk Factors
  • Uterus / blood supply
  • Vasoconstrictor Agents / adverse effects
  • Vasoconstrictor Agents / pharmacology
  • Vasoconstrictor Agents / therapeutic use*

Substances

  • Vasoconstrictor Agents
  • Ephedrine
  • Epinephrine