Insights from the genome of a high alkaline cellulase producing Aspergillus fumigatus strain obtained from Peruvian Amazon rainforest

J Biotechnol. 2017 Jun 10:251:53-58. doi: 10.1016/j.jbiotec.2017.04.010. Epub 2017 Apr 12.

Abstract

Here, we report the complete genome sequence of a high alkaline cellulase producing Aspergillus fumigatus strain LMB-35Aa isolated from soil of Peruvian Amazon rainforest. The genome is ∼27.5mb in size, comprises of 228 scaffolds with an average GC content of 50%, and is predicted to contain a total of 8660 protein-coding genes. Of which, 6156 are with known function; it codes for 607 putative CAZymes families potentially involved in carbohydrate metabolism. Several important cellulose degrading genes, such as endoglucanase A, endoglucanase B, endoglucanase D and beta-glucosidase, are also identified. The genome of A. fumigatus strain LMB-35Aa represents the first whole sequenced genome of non-clinical, high cellulase producing A. fumigatus strain isolated from forest soil.

Keywords: Amazon rainforest; Aspergillus fumigatus; CAZymes; Lignocellulolytic enzyme; Whole genome sequence.

MeSH terms

  • Aspergillus fumigatus / genetics*
  • Aspergillus fumigatus / metabolism
  • Cellulase / metabolism
  • Genome, Fungal*
  • Peru
  • Phylogeny
  • Rainforest
  • Soil Microbiology

Substances

  • Cellulase