An overview application of silver nanoparticles in inhibition of herpes simplex virus

Artif Cells Nanomed Biotechnol. 2018 Mar;46(2):263-267. doi: 10.1080/21691401.2017.1307208. Epub 2017 Apr 12.

Abstract

Nanoscale particles and molecules are a potential different for the treatment of disease because they have distinctive biologic property based on their structure and size, which is different from traditional small-molecule drugs. The antimicrobial mechanisms of silver nanoparticles include the formation of free radicals damaging the bacterial membranes, interactions with DNA, adhesion to cell surface altering the membrane properties, and enzyme damage. In this review, we focus on applications of silver nanoparticles in inhibition of herpes simplex virus.

Keywords: Antimicrobial activity; herpes simplex virus; nanomaterials; silver nanoparticles.

Publication types

  • Review

MeSH terms

  • Antiviral Agents / chemistry*
  • Antiviral Agents / pharmacology*
  • Herpes Simplex / epidemiology
  • Herpes Simplex / etiology
  • Humans
  • Metal Nanoparticles*
  • Silver / chemistry*
  • Silver / pharmacology*
  • Simplexvirus / drug effects*
  • Simplexvirus / physiology

Substances

  • Antiviral Agents
  • Silver